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Patrick S. Kamath, MD (he/him/his)

Professor of Medicine
Mayo Clinic College of Medicine and Science
Rochester, MN

Patrick S. Kamath, MD, is a professor of medicine that focuses on acute-on-chronic liver failure, nonalcoholic fatty liver disease, polycystic liver disease, Budd-Chiari syndrome, and hereditary hemorrhagic telangiectasia. Dr. Kamath also studies alcohol associated hepatitis, cirrhosis, and the complications thereof, including portal hypertension, variceal hemorrhage, ascites, and hepatic encephalopathy. Dr. Kamath has contributed to recently published research on management of acute-on-chronic liver failure and on prevention and treatment of cirrhotic complications, including management of hepatic encephalopathy in the hospital, primary prophylaxis of variceal bleeding, and prevalence and prediction factors of infections in patients with cirrhosis. He and his co-workers were instrumental in developing the Model for End-Stage Liver Disease (MELD) score, which is used worldwide to determine prognosis in liver disease and prioritize organ allocation for liver transplantation. Dr. Kamath serves as a co-investigator in the AlkHepNet consortium, a multi-center collaboration aimed at improving understanding of alcohol associated hepatitis and developing novel therapies to treat it. The consortium is funded by the National Institutes of Health. Dr. Kamath works to improve understanding of the mechanisms and complications of liver disease, in the hopes of developing new strategies of prevention and treatment that will improve quality of life and overall outcomes for patients with various liver diseases. The MELD score that he helped develop is used worldwide as a prognostic score for liver disease. His current focus is on finding ways to improve survival in patients with acute-on-chronic liver failure. He is also dedicated to the education of the next generation of physicians, who will further advance this work.

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